个人简历：

郭有，男，汉族，中共党员，山西临猗人，副教授。硕士研究生导师。2025年获得赣南医科大学三育人先进个人，现任赣南医科大学第一附属医院医药大数据中心负责人，江西省医学会医学科研管理分会副主任委员，中国研究型医院学会临床数据与样本资源专业委员会常委。2018年毕业于福建医科大学，取得博士学位。近五年来，承担国家自然科学基金1项，江西省重点研发计划1项；获得江西省自然科学奖1项；发表SCI学术论文30余篇。

学习工作经历：

2000.09—2005.07  山西医科大学第一临床医学院临床医学专业本科生；

2005.09—2008.07  贵州医科大学公共卫生学院流行病与卫生统计学研究生；

2015.09—2018.07  福建医科大学计算生物与生物信息学博士生；

2018.07至今    赣南医科大学第一附属医院（第一临床医学院）

荣誉称号：

1.2026年荣获赣南医科大学优秀共产党员。

研究方向：

基于医疗可信数据空间建设，面向真实世界证据的医疗大数据研究。

科研课题：

1. 国家自然科学基金委员会, 地区科学基金项目, 82060618, 基于转录组特征构建局部进展期直肠癌淋巴转移和全辅助治疗后完全缓解的联合预测模型, 2021-01-01 至 2024-12-31, 35万元, 主持；

2.江西省科技厅, 重点研发计划, 20203BBGL73184, 局部进展期直肠癌全辅助治疗的联合诊疗标志构建与验证, 2020-12 至 2023-12, 10万元,主持。

发表文章：

1：Zhao Q, Zhang C, Jiang W, Liu W, Shi F, Liu C, Ouyang M, Guo Y. Association of the C-reactive protein-triglyceride-glucose index with the risk of incident cardiovascular disease in rectal cancer survivors. Front Cardiovasc Med. 2026 Jul 29;13:1880389. doi: 10.3389/fcvm.2026.1880389

2：Zhao Q, Jiang W, Zhang C, Ouyang M, Wu N, Guo Y. Advancing health equity in proactive health management: from data underrepresentation and algorithmic bias to a closed-loop governance framework. Front Public Health. 2026 Jun 17;14:1863050. doi: 10.3389/fpubh.2026.1863050

3：Shi F, Liu C, Liu W, Cai H, Zhao Q, Zhang C, Liu Q, Wu N, Guo Y. Triglyceride-glucose index and atherogenic index of plasma as predictors of cardiovascular risk in rectal cancer survivors. Front Cardiovasc Med. 2026 Mar 9;13:1707899. doi: 10.3389/fcvm.2026.1707899

4：Zhao Q, Zhang C, Zhang W, Zhang S, Liu Q, Guo Y. Applications and challenges of biomarker-based predictive models in proactive health management. Front Public Health. 2025 Aug 18;13:1633487. doi: 10.3389/fpubh.2025.1633487

5：Meng J, Wu M, Shi F, Xie Y, Wang H, Guo Y. Medical laboratory data-based models: opportunities, obstacles, and solutions. J Transl Med. 2025 Jul 24;23(1):823.  

6：Liu W, Cao S, Guo Y, Gao Y, Zhang X, Shi D, Huang L. Associations of perchlorate, nitrate, and thiocyanate with oxidative stress, inflammatory, and lung diseases: Evidence from a nationally representative population-based study. Environ Pollut. 2025 Jul 30; 383:126929.  

7: Qian C, Yang S, Chen Y, Ge R, Shi F, Liu C, Wang H, Guo Y. Predicting pathological response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer with two step feature selection and ensemble learning. Sci Rep. 2025 Mar 22;15(1):9936. doi: 10.1038/s41598-025-94337-y.  

8: Yang C, Chen Y, Qian C, Shi F, Guo Y. The data-intensive research paradigm: challenges and responses in clinical professional graduate education. Front Med (Lausanne). 2025 Feb 7;12:1461863. doi: 10.3389/fmed.2025.1461863.  

9: Qiao H, Chen Y, Qian C, Guo Y. Clinical data mining: challenges, opportunities, and recommendations for translational applications. J Transl Med. 2024 Feb 20;22(1):185. doi: 10.1186/s12967-024-05005-0.  

10: Qiao H, Wang C, Yang C, Lei L, Chen Y, Luo Y, Zeng X, Guo Y. Association between increased C-reactive protein and cardiovascular disease among patients with rectal cancer. Front Oncol. 2023 Nov 22; 13: 1287619. doi:10.3389/fonc.2023.1287619.

11: Peng W, Qiao H, Mo L, Guo Y. Progress in the diagnosis of lymph node metastasis in rectal cancer: a review. Front Oncol. 2023 Jul 13;13:1167289. doi:10.3389/fonc.2023.1167289.  

12: Li H, Ma L, Luo F, Liu W, Li N, Hu T, Zhong H, Guo Y, Hong G. Construct of qualitative diagnostic biomarkers specific for glioma by pairing serum microRNAs. BMC Genomics. 2023 Mar 2;24(1):96. doi: 10.1186/s12864-023-09203-w.13: Xue Z, Yang S, Luo Y, He M, Qiao H, Peng W, Tong S, Hong G, Guo Y. Animmuno-score signature of tumor immune microenvironment predicts clinical outcomes in locally advanced rectal cancer. Front Oncol. 2022 Sep 29;12:993726.doi:10.3389/fonc.2022.993726.  

14: Hong G, Luo F, Chen Z, Ma L, Lin G, Wu T, Li N, Cai H, Hu T, Zhong H,Guo Y, Li H. Predict ovarian cancer by pairing serum miRNAs: Construct of single sample classifiers. Front Med (Lausanne). 2022 Aug 2; 9: 923275.doi:10.3389/fmed.2022.923275.  

15: Xue Z, Yang S, Luo Y, Cai H, He M, Ding Y, Lei L, Peng W, Hong G, Guo Y. A 41-Gene Pair Signature for Predicting the Pathological Response of Locally Advanced Rectal Cancer to Neoadjuvant Chemoradiation. Front Med (Lausanne).2021 Sep 14;8:744295. doi: 10.3389/fmed.2021.744295.  

16: Li H, Jiang F, Du Y, Li N, Chen Z, Cai H, Guo Y, Hong G. Identification of differential DNA methylation alterations of ovarian cancer in peripheral whole blood based on within-sample relative methylation orderings. Epigenetics. 2022 Mar;17(3):314-326. doi: 10.1080/15592294.2021.1900029. E.

编写教材（著作）：

1.大数据时代下的临床科研数据挖掘（主编），江西科学技术出版社，2022年.

联系方式：

电子邮箱：gy@gmu.edu.cn